Clostridioides difficile Infection in the Stem Cell Transplant and Hematologic Malignancy Population
نویسندگان
چکیده
منابع مشابه
Mortality in hematologic malignancy and hematopoietic stem cell transplant patients with mucormycosis, 2001 to 2009.
Mortality due to mucormycosis is high. We assessed clinical characteristics and mortality among stem cell transplant and hematologic malignancy patients diagnosed with mucormycosis from 2001 to 2009. Thirty patients were diagnosed with probable or proven mucormycosis during the study. Twenty-six were diagnosed premortem, and most were treated with liposomal amphotericin B single-agent antifunga...
متن کاملClostridium difficile infection and limitations of markers for severity in patients with hematologic malignancy.
OBJECTIVE To describe characteristics of Clostridium difficile infection (CDI) and markers of severe CDI among patients with hematologic malignancies. DESIGN Case-control study. SETTING Tertiary care teaching hospital. PATIENTS AND METHODS Inpatients with hematologic malignancies and CDI were age and time matched with 2 control inpatients without hematologic malignancies. Chart reviews we...
متن کاملClostridium difficile Infection in Solid Organ and Haematopoietic Stem Cell Transplant Recipients
Patients undergoing solid organ and stem cell transplantation are at increased risk of Clostridium difficile infection (CDI) compared with nontransplant patients. CDI may be associated with significant morbidity in this population including prolonged hospitalization, increased hospital charges, and complications in the transplanted organ. A combination of host factors, including both B-cell and...
متن کاملClostridioides difficile Biology: Sporulation, Germination, and Corresponding Therapies for C. difficile Infection
Clostridioides difficile is a Gram-positive, spore-forming, toxin-producing anaerobe, and an important nosocomial pathogen. Due to the strictly anaerobic nature of the vegetative form, spores are the main morphotype of infection and transmission of the disease. Spore formation and their subsequent germination play critical roles in C. difficile infection (CDI) progress. Under suitable condition...
متن کاملRisk factors for recurrent Clostridium difficile infection in hematopoietic stem cell transplant recipients.
BACKGROUND Recurrent Clostridium difficile infection (CDI) represents a significant burden on the healthcare system and is associated with poor outcomes in hematopoietic stem cell transplant (HSCT) patients. Data are limited evaluating recurrence rates and risk factors for recurrence in HSCT patients. METHODS HSCT patients who developed CDI between January 2010 and December 2012 were divided ...
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ژورنال
عنوان ژورنال: Infectious Disease Clinics of North America
سال: 2019
ISSN: 0891-5520
DOI: 10.1016/j.idc.2019.02.010